Confirm the checked and carry-on baggage allowances directly with the airline before booking, as small carriers often have different rules and fees than major airlines.
Reconfirm departure times shortly before travel and allow extra connection time, since regional schedules can change with limited options for alternatives.
Bring printed copies of your booking and travel documents in addition to electronic versions, because airport staff at smaller operators may have limited systems access.
Expect limited onboard amenities and catering on short regional sectors, so pack snacks and any essentials you may need during the flight.
Arrive at the airport earlier than you would for a major carrier to complete check-in and any manual processing, and have local currency or a widely accepted card for fees or purchases.